Skip to content

FAQs

Frequently asked questions (FAQs) about XCOPRI

Whether you are just starting your journey or are well on the road to seizure reduction, it is normal to have questions. Here are the answers to some FAQs people have about XCOPRI. Remember to always check in with your doctor as your primary source of medical information and guidance.

Basic information about XCOPRI.

XCOPRI® (cenobamate tablets) CV is a prescription medicine taken by mouth once daily to treat partial-onset seizures in adults.

XCOPRI® (cenobamate tablets) CV can be purchased at any retail pharmacy. It is also available through Specialty Pharmacy options, Amazon Pharmacy home delivery, and Omni by ScriptDrop home delivery.

XCOPRI Savings and Resources

First, talk with your doctor and ask if XCOPRI® (cenobamate tablets) CV might be a good fit for you.

Next, click the button below to download the XCOPRI $0 Trial Offer.* Save the offer to your phone or print it and bring it with you to the pharmacy with your first month’s prescription of XCOPRI (12.5/25 mg).

*Terms, conditions, and eligibility requirements apply.

Download Trial Offer

SK Life Science Navigator can help people who are prescribed XCOPRI® (cenobamate tablets) CV get started and continue on therapy as appropriate. Navigator can help:

  • Find out if XCOPRI is covered by your insurance
  • Supply XCOPRI to eligible people starting treatment, experiencing coverage delays, or who are uninsured or underinsured
  • Assist you in locating XCOPRI
  • Provide prior authorization information for XCOPRI if required
XCOPRI Savings and Resources

Taking XCOPRI.

XCOPRI® (cenobamate tablets) CV is a prescription medicine taken by mouth once daily to treat partial‑onset seizures in adults.

Taking XCOPRI

The recommended starting dose is 12.5 mg once daily. You'll start on the lowest dose and increase in 2-week intervals, until you reach the dose that's right for you. If your doctor decides to increase your dose to more than 100 mg, you can increase it by 50 mg/day every 2 weeks. However, your daily dose should not exceed 400 mg. Your doctor will help you find an effective daily dose, typically between 100 mg and 400 mg per day.

Learn About Once-Daily Dosing

Everyone is different. If you and your doctor decide to add XCOPRI® (cenobamate tablets) CV to your treatment for partial-onset seizures, you will start on the lowest dose and your doctor will slowly increase your dose over time until you reach one that’s right for you.

See Clinical Results With XCOPRI

Taking XCOPRI with other medications.

People participating in the clinical trials with XCOPRI® (cenobamate tablets) CV were also on additional medications.

If you are already taking medication for your partial-onset seizures, talk with your doctor about what adding XCOPRI could mean for you.

XCOPRI® (cenobamate tablets) CV may affect the way other medicines work, and other medicines may affect how XCOPRI works. Do not start or stop other medicines without talking with your doctor. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

XCOPRI® (cenobamate tablets) CV may cause your birth control medicine to be less effective. Talk with your doctor about the best birth control method for you to use.

XCOPRI side effects.

Side effects may include:

  • Feeling sleepy and tired
  • Dizziness
  • Double vision
  • Headache

If you experience any side effects that bother you, be sure to discuss them with your doctor.

It is important to pay attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings, and report any to your doctor. XCOPRI® (cenobamate tablets) CV can cause serious or life-threatening side effects.

Call your doctor or 911 right away if you experience reactions such as a skin rash, hives, fever, or swelling of the face, eyes, lips, or tongue.

These are not all the possible side effects of XCOPRI. A full description of side effects can be found in the Medication Guide and Important Safety Information.

Before starting once-daily XCOPRI, it’s important to let your doctor know if you have been diagnosed with a genetic problem that affects your heart (called Familial Short QT syndrome). Do not take XCOPRI if you have Familial Short QT syndrome.

Learn More About Taking XCOPRI

Understanding epilepsy.

Epilepsy is a chronic condition of the brain that causes repeated seizures, and is usually defined as 2 or more seizures with no obvious cause at least 24 hours apart. Epilepsy is quite common, affecting at least 3 million adults in the United States.

The risk of developing epilepsy as a result of genetics may be possible. Other causes of epilepsy can include:

  • Head trauma, perhaps as the result of an accident or other traumatic injury
  • Brain conditions. Strokes are the leading cause of epilepsy in adults older than age 35
  • Prenatal injury such as oxygen deficiency or poor nutrition
  • Infectious diseases, such as meningitis and viral encephalitis
Learn More in This Video

Epilepsy is treated by doctors who specialize in conditions of the brain or epilepsy, such as a neurologist or epileptologist.

Learning about seizures.

A seizure is caused by a sudden surge of electrical activity in the brain. Seizures can last anywhere from a few seconds to a few minutes.

There are 2 main categories of seizures:

  • Generalized seizures affect both sides of the brain from the start of the seizure
  • Partial-onset or focal seizures begin in 1 area of the brain. About 60% of people with epilepsy have this type of seizure
Learn More in This Video

Different people can have very different triggers. Here are some that are common:

  • Missed medication is one of the main reasons for breakthrough seizures in people whose seizures were under control. It’s important to take seizure medication as prescribed by your doctor
  • Lack of sleep can lead to more seizures and increase their intensity and duration
  • Stress can trigger seizures in people with epilepsy
  • Alcohol-related seizures usually occur when a large amount is consumed within a short period of time or during withdrawals, which can be up to 72 hours after drinking
  • Among women of childbearing age who have epilepsy, nearly half experience increased seizures around the time of their period
  • Not eating well or low blood sugar
  • Specific foods, excess caffeine, or other products that may make seizures worse
  • Use of certain medications
  • Fever or other illness-related symptoms
  • Flashing and/or bright lights or patterns

Some basic things you can do for someone having a seizure are:

  • Turn them on their side if they are not aware/alert
  • Keep their airway clear
  • Loosen tight clothes around their neck
  • Put something small and soft under their head
  • If their seizure lasts more than 5 minutes, call 911

Partial-onset (focal) seizures.

A partial-onset or focal seizure is the most common type of seizure in many people living with epilepsy. About 60% of people living with epilepsy experience this type of seizure. Partial-onset seizures begin in 1 part of the brain. They generally last from a few seconds to a few minutes.

During a simple-partial or focal-aware seizure, a person is alert and aware of what is going on around them.


During a complex-partial or focal impaired-awareness seizure, a person may appear confused, dazed, and unaware of their surroundings.

Sometimes the first symptom of a seizure is an aura, a sensation that feels different. It serves as a warning that a seizure is about to occur and may remind you to find a safe place until the seizure passes. Symptoms can vary depending on which lobe, or area, of the brain is affected and the functions that area controls: the frontal lobe, the temporal lobe, the parietal lobe, and the occipital lobe.

Learn More in This Video

Glossary: Key terms explained

An advocate is a person who speaks or writes in support of another person or cause.
Epilepsy is a condition of the brain that causes a person to have seizures.
Epilepsy medicine is medication used to treat different types of seizures. It may be called an antiepileptic drug (AED) and is also referred to as an anti-seizure medication (ASM).
An epileptologist is a neurologist who specializes in epilepsy.
A neurologist is a doctor who specializes in treating conditions of the nervous system.
Side effects are unwanted symptoms caused by medical treatment.
Triggers are events that may occur fairly regularly before seizures and more often than by chance.

XCOPRI is proven to significantly reduce seizures.

Learn more about how well it can work

See the Results

Hear stories from people who take XCOPRI.

Each journey is unique and inspiring

Explore Patient Videos
INDICATION

XCOPRI® (cenobamate tablets) CV is a prescription medicine used to treat partial-onset seizures in adults.

IMPORTANT SAFETY INFORMATION

DO NOT TAKE XCOPRI IF YOU:

  • Are allergic to cenobamate or any of the other ingredients in XCOPRI.
  • Have a genetic problem (called Familial Short QT syndrome) that affects the electrical system of the heart.

IMPORTANT SAFETY INFORMATION and INDICATION for XCOPRI® (cenobamate tablets) CV

DO NOT TAKE XCOPRI IF YOU:

  • Are allergic to cenobamate or any of the other ingredients in XCOPRI.
  • Have a genetic problem (called Familial Short QT syndrome) that affects the electrical system of the heart.

XCOPRI CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING:

Allergic reactions: XCOPRI can cause serious skin rash or other serious allergic reactions which may affect organs and other parts of your body like the liver or blood cells. You may or may not have a rash with these types of reactions. Call your healthcare provider right away and go to the nearest emergency room if you have any of the following: swelling of your face, eyes, lips, or tongue, trouble swallowing or breathing, a skin rash, hives, fever, swollen glands, or sore throat that does not go away or comes and goes, painful sores in the mouth or around your eyes, yellowing of your skin or eyes, unusual bruising or bleeding, severe fatigue or weakness, severe muscle pain, frequent infections, or infections that do not go away. Take XCOPRI exactly as your healthcare provider tells you to take it. It is very important to increase your dose of XCOPRI slowly, as instructed by your healthcare provider.

QT shortening: XCOPRI may cause problems with the electrical system of the heart (QT shortening). Call your healthcare provider if you have symptoms of QT shortening including fast heartbeat (heart palpitations) that last a long time or fainting.

Suicidal behavior and ideation: Antiepileptic drugs, including XCOPRI, may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying; attempting to commit suicide; new or worse depression, anxiety, or irritability; feeling agitated or restless; panic attacks; trouble sleeping (insomnia); acting aggressive; being angry or violent; acting on dangerous impulses; an extreme increase in activity and talking (mania); or other unusual changes in behavior or mood.

Nervous system problems: XCOPRI may cause problems that affect your nervous system. Symptoms of nervous system problems include: dizziness, trouble walking or with coordination, feeling sleepy and tired, trouble concentrating, remembering, and thinking clearly, and vision problems. Do not drive, operate heavy machinery, or do other dangerous activities until you know how XCOPRI affects you.

Do not drink alcohol or take other medicines that can make you sleepy or dizzy while taking XCOPRI without first talking to your healthcare provider.

DISCONTINUATION:

Do not stop taking XCOPRI without first talking to your healthcare provider. Stopping XCOPRI suddenly can cause serious problems. Stopping seizure medicine suddenly in a patient who has epilepsy can cause seizures that will not stop (status epilepticus).

DRUG INTERACTIONS:

XCOPRI may affect the way other medicines work, and other medicines may affect how XCOPRI works. Do not start or stop other medicines without talking to your healthcare provider. Tell healthcare providers about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

PREGNANCY AND LACTATION:

XCOPRI may cause your birth control medicine to be less effective. Talk to your healthcare provider about the best birth control method to use.

Talk to your healthcare provider if you are pregnant or plan to become pregnant. It is not known if XCOPRI will harm your unborn baby. Tell your healthcare provider right away if you become pregnant while taking XCOPRI. You and your healthcare provider will decide if you should take XCOPRI while you are pregnant. If you become pregnant while taking XCOPRI, talk to your healthcare provider about registering with the North American Antiepileptic Drug (NAAED) Pregnancy Registry. The purpose of this registry is to collect information about the safety of antiepileptic medicine during pregnancy. You can enroll in this registry by calling 1‑888‑233‑2334 or go to www.aedpregnancyregistry.org.

Talk to your healthcare provider if you are breastfeeding or plan to breastfeed. It is not known if XCOPRI passes into breastmilk. Talk to your healthcare provider about the best way to feed your baby while taking XCOPRI.

COMMON SIDE EFFECTS:

The most common side effects in patients taking XCOPRI include dizziness, sleepiness, headache, double vision, and feeling tired.

These are not all the possible side effects of XCOPRI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1‑800‑FDA‑1088 or at www.fda.gov/medwatch.

DRUG ABUSE:

XCOPRI is a federally controlled substance (CV) because it can be abused or lead to dependence. Keep XCOPRI in a safe place to prevent misuse and abuse. Selling or giving away XCOPRI may harm others and is against the law.

INDICATION:

XCOPRI is a prescription medicine used to treat partial-onset seizures in adults 18 years of age and older.

It is not known if XCOPRI is safe and effective in children under 18 years of age.

Please see additional patient information in the Medication Guide. This information does not take the place of talking with your healthcare provider about your condition or your treatment.

Please see full Prescribing Information and Medication Guide.